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WebUnbalanced Th1/Th2 T-cell responses in the liver are a characteristic of hepatic inflammation and subsequent liver fibrosis. The recently discovered Th17 cells, a subtype of CD4+T-helper cells mainly producing IL-17 and IL-22, have initially been Web13. jún 2024 · Microscopic examination reveals perivenular sinusoidal congestion and increased pigment in the hepatocytes; prolonged cardiac failure can lead to liver cell necrosis and focal inflammatory infiltrates, as well as perivenular fibrosis extending to … WebThere is increasing interest in the role of ductular reaction as part of the pathogenesis and characteristic histology of non-alcoholic steatohepatitis. However, earlier studies did not separately assess the contribution of periportal and centrilobular zone ductular reaction over the spectrum of non-alcoholic steatohepatitis, and their clinical significance remains … crispy plotter