Webbför 2 dagar sedan · One of the main problems in chemotherapy using platinum drugs as … WebbKey Points. Cisplatin, a chemotherapy drug, is best known for curing testicular cancer.; Prior to the discovery of cisplatin, men with testicular cancer had few medical options. Cisplatin is also used in the treatment …

Cisplatin: The first metal based anticancer drug - ScienceDirect

Webb17 jan. 2024 · A simple, sensitive and repeatable D 2 O-single cell Raman spectroscopy method is developed to quantify the inhibitory activity of anticancer drugs on cancer cell metabolism. The IC 50 values obtained from A549 cells incubated with cisplatin and taxol are comparable with results of CCK-8 and ATP luminescent cell viability assays. WebbCisplatin has been clinically used as an anticancer drug and a radiosensitizer. Cisplatin can induce cell-cycle arrest, inhibit DNA replication, and trigger apoptosis as well as Auger electron generation owing to the high Z number of platinum. Nonetheless, the use of free cisplatin in chemoradiotherapy is limited owing to its toxicity ... cipher police

Platinum-based drugs for cancer therapy and anti-tumor strategies

WebbCisplatin, cis-diamminedichlorido-platinum(II), is an important therapeutic tool in the … Webb8 sep. 2024 · Point out that cisplatin does not work for all types of cancer and that lots of anticancer drugs have been developed since cisplatin. Use the article and resource designing anticancer drugs and follow up with the worksheet above, to help students apply their knowledge of cisplatin to other platinum anticancer drugs and gain an … WebbDescription. 30 years after its discovery as an antitumor agent, cisplatin represents today … dialyse harz